Hairy cell leukemia: present and future directions

B-Cell Chronic Lymphocytic Leukemia: Present Status and Future Directions

INCE TURKS’ initial identification of chronic lymphoS cytic leukemia (CLL), Minot and Isaacs” description of its clinical features in 1924, and Dameshek‘? hypothesis in 1967, considerable progress in the understanding of CLL has been achieved, especially during the last two decades. The purpose of the present work is to review the major advances in the biology and clinical research of CLL and t...

B-cell chronic lymphocytic leukemia: present status and future directions. French Cooperative Group on CLL.

INCE TURKS’ initial identification of chronic lymphoS cytic leukemia (CLL), Minot and Isaacs” description of its clinical features in 1924, and Dameshek‘? hypothesis in 1967, considerable progress in the understanding of CLL has been achieved, especially during the last two decades. The purpose of the present work is to review the major advances in the biology and clinical research of CLL and t...

Clinical reasoning assessment through medical expertise theories: past, present and future directions

  Exploration into the concept of "medical expert" dates back to more than 50 years ago, yet yielding three leading theories in the area of clinical reasoning, namely, knowledge structure, hypothetic-deductive, and dual process. Each theory defines “medical expert” in a dissimilar way. Therefore, the methods of assessment through which the experts are identified have been changed during the tim...

Hairy cell leukemia-variant.

Hairy cell leukaemia variant is a very rare chronic lymphoproliferative disorder and is closely related to hairy cell leukemia. We hereby describe a case of hairy cell leukaemia variant for the first time in Saudi Arabia. An elderly Saudi man presented with pallor, massive splenomegaly, and moderate hepatomegaly. Hemoglobin was 7.7 g/dl, Platelets were 134 x109/l and white blood count was 140x1...

Simultaneous Multithreading: Present Developments and Future Directions